Remains of tobacco leaves and pipes are found in Egyptian mummies. This is yet to be explained scientifically.
Pipes are used by North American Indians for ceremonial purposes and as a symbol of reconciliation.
The Greek doctor Hippocrates used smoke inhalation from herbs as a remedy for certain female diseases.
The herb "Angelikarot" is smoked in pipes in Norway.
Columbus discovers (or maybe rediscovers) America and the use of tobacco.
The tobacco plant reaches Europe.
Jean Nicot launches the tobacco plant as a multiremedy; among the French royals, it becomes fashionable to "sneeze away the headache".
Chalk pipes are mass-produced - mostly for mariners.